The Lancaster County Sheriff's Office investigated a two vehicle, injury crash on Highway 43, between Roca Road and Wittstruck Road. Bennet Fire and Rescue, Lincoln Fire and Rescue and Star Care also responded.
Roger Hoback, age 58, of Nebraska City was driving his red, 2015 Nissan Altima northbound on Hwy 43 when he crossed the left of center.
Police say he then struck a southbound Peterbilt semi-truck head-on driven by Brandon Parker, age 47 of Firth.
Parker suffered minor injuries and was not required to be transported to the hospital from the scene.
Police say Hoback was transported to Bryan Medial Center West Campus by Star Care with serious injuries.
The Lancaster County Sheriff's office says Hoback died July 4th as a result of complications involving his injuries. Hoback's family has been notified of his death.
Authorities say there are no indications of impairment, neither drugs nor alcohol, and seatbelts were in use.
The crash remains under investigation.